Paula Seibold
Friedrich Schiller University
Pharmaceutical Microbiology
Stimulation of basidiomycete indoleethylamine metabolism by spatiotemporal light and temperature gradients
The proposed work investigates the molecular mechanism how psilocybin/indoleethylamine biosynthesis is regulated and transcriptionally and/or post-transcriptionally controlled. The project falls into the Structured Surfaces Microhabitat theme...
PhD start: 04/01/2021
Publications
Seibold PS, Lawrinowitz S, Raztsou I, Gressler M, Arndt HD, Stallforth P, Hoffmeister D 2023 Bifurcate evolution of quinone synthetases in basidiomycetes. Fungal Biol Biotechnol 10, 14-14.
Gressler M, Löhr NA, Schäfer T, Lawrinowitz S, Seibold PS, Hoffmeister D 2021 Mind the mushroom: natural product biosynthetic genes and enzymes of Basidiomycota. Nat Prod Rep 38, 702-722.
Seibold PS, Lenz C, Gressler M, Hoffmeister D 2020 The Laetiporus polyketide synthase LpaA produces a series of antifungal polyenes. J Antibiot (Tokyo) 73, 711-720.