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Candida Species-Dependent Release of IL-12 by Dendritic Cells Induces Different Levels of NK Cell Stimulation.
Marolda A, Hünniger K, Böttcher S, Vivas W, Löffler J, Figge MT, Kurzai O2020Candida Species-Dependent Release of IL-12 by Dendritic Cells Induces Different Levels of NK Cell Stimulation. J Infect Dis 221, 2060-2071.
Abstract
Candida albicans and Candida glabrata are the 2 most prevalent Candida species causing bloodstream infections. Patterns of innate immune activation triggered by the 2 fungi differ considerably.
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Doctoral researchers
Dr. rer. nat. Alessandra Marolda
Characterizing innate immune cell activation by fungal pathogens using Live Cell Imaging
Leibniz Institute for Natural Product Research and Infection Biology – Hans Knöll Institute (HKI)
Applied Systems Biology
Dr. rer. nat. Wolfgang Vivas
Modulation of Dendritic Cell Function by the fungal Quorum Sensing Molecule Farnesol
